GLOBAL ANDROLOGY FORUM
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Sperm Morphology Assessment in the Era of Intracytoplasmic Sperm Injection: Reliable Results Require Focus on Standardization, Quality Control, and Training.
Jun 11, 2023
Sperm Morphology Assessment in the Era of Intracytoplasmic Sperm Injection: Reliable Results Require Focus on Standardization, Quality Control, and Training.
Agarwal A, Sharma R, Gupta S, Finelli R, Parekh N, Panner Selvam MK, Henkel R, Durairajanayagam D, Pompeu C, Madani S, Belo A, Singh N, Covarrubias S, Darbandi S, Sadeghi R, Darbandi M, Vogiatzi P, Boitrelle F, Simopoulou M, Saleh R, Arafa M, Majzoub A, Kandil H, Zini A, Ko E, Alvarez JG, Martinez M, Ramsay J, Jindal S, Busetto GM, Sallam H, Maldonado I, Anagnostopoulou C, Alves MG, Sengupta P, Gilany K, Evenson DP, Lewis SE, Gosalvez J, Ambar RF, Shah R.World J Mens Health. 2022 Jul;40(3):347-360.
CAPSULE:
This review aims to cover several key aspects related to the evaluation and management of sperm morphology. Firstly, it summarizes the standardized laboratory procedures necessary for an accurate assessment of sperm morphology, emphasizing the importance of consistent training and monitoring, as well as the use of an ocular micrometer for precise measurement of sperm dimensions. The review also highlights the significance of quality control (QC) and quality assurance (QA) in the laboratory assessment of sperm morphology, as they are crucial for reliable and dependable results, and play a role in laboratory accreditation. Furthermore, the association between abnormal sperm morphology, also known as teratozoospermia, and the outcomes of assisted reproductive technology (ART) is discussed. The review explores how abnormal sperm morphology can impact the success of ART procedures, emphasizing the importance of considering sperm morphology in the clinical management of infertile couples and their choice of ART. In conclusion, this comprehensive review underscores the importance of specialized laboratory skills, QC, and QA in evaluating sperm morphology. It highlights the need for accurate measurement techniques, prompt identification and rectification of errors, and the use of proficiency testing for reporting reliable results. Understanding sperm morphology is crucial in the clinical management of infertility and in making informed decisions regarding ART procedures.
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